Table 2.

Joint effects of vaccination with BCG and/or vaccinia with history of serious infectious disease on melanoma risk^a

Co-variable serious infectious disease	Vaccination with BCG and vaccinia		Concomitant effect (type of)
	Yes	No
≥1	1.00 n = 96	1.21 ((0.67-2.06) n = 12
0	1.12 (0.30-4.30) n = 516	3.03 (1.58-5.97) n = 88	Cumulative
	Vaccination with BCG or vaccinia
Serious infectious disease
	Yes	No
≥1	1.00 n = 98	1.97 (1.14-3.56) n = 12
0	1.28 (0.35-4.90) n = 420	3.45 (1.79-6.80) n = 89	Cumulative

^aData expressed as Odds Ratios (95% Confidence intervals), adjusted for centre, sex, age, ethnic origin, skin type, freckling index, number of naevi and number of sunburns. n = number of cases and controls. Summarized from the FEBIM study [82, 83].