Table 4.
Gene expression in distal ileum and proximal colon for experimental diet groups relative to control (CONT) group
|
Gene1 |
Group2 |
Gene expression3 |
|
|---|---|---|---|
| Distal ileum | Proximal colon | ||
| ffar2 |
CELL |
1.16 (0.12-5.16) |
1.24 (0.20-3.14) |
| |
FOS |
2.15 (0.73-7.05)** |
1.02 (0.33-3.10) |
| |
GLUC |
1.07 (0.33-3.81) |
1.07 (0.43-2.97) |
| |
PECT |
1.23 (0.42-7.31) |
0.63 (0.13-2.48) |
| ffar3 |
CELL |
1.40 (0.15-14.72) |
0.68 (0.14-3.58) |
| |
FOS |
1.11 (0.21-9.44) |
0.42 (0.06-2.39)* |
| |
GLUC |
0.49 (0.02-4.91) |
0.63 (0.10-7.68) |
| |
PECT |
1.15 (0.13-11.39) |
0.42 (0.09-1.85)** |
| sucnr1 |
CELL |
3.59 (0.17-33.62)* |
4.13 (0.47-52.44)** |
| |
FOS |
0.70 (0.03-11.53) |
0.82 (0.06-8.85) |
| |
GLUC |
1.75 (0.06-23.59) |
1.65 (0.11-56.72) |
| |
PECT |
0.95 (0.01-16.54) |
0.79 (0.04-14.45) |
| GLP-1 |
CELL |
0.81 (0.34-2.01) |
0.71 (0.13-4.48) |
| |
FOS |
0.79 (0.23-1.93) |
1.54 (0.35-9.73) |
| |
GLUC |
0.78 (0.35-1.69) |
1.82 (0.43-10.01) |
| |
PECT |
0.53 (0.03-1.71)* |
1.18 (0.15-8.77) |
| PYY |
CELL |
0.97 (0.46-2.50) |
0.62 (0.30-1.32)* |
| |
FOS |
0.91 (0.24-2.74) |
0.78 (0.32-3.71) |
| |
GLUC |
0.79 (0.32-2.16) |
1.11 (0.30-3.18) |
| PECT | 0.40 (0.00-1.75)* | 0.71 (0.11-2.70) | |
1Abbreviations are: ffar free fatty acid receptor, sucnr succinate receptor, GLP-1 glucagon-like peptide-1, PYY peptide tyrosine tyrosine.
2Groups were given diets containing 10% w/w fibre as cellulose (CELL), fructo-oligosaccharide (FOS), oat beta-glucan (GLUC) or apple pectin (PECT); n = 10/group.
3Values are medians (with 95% C.I.) as determined by REST-2009 [32]. *P < 0.05, **P < 0.01.