Table 1. Stem cells involved in liver physiopathology.
Stem cell | Markers | Origin | Location | Stimulus |
---|---|---|---|---|
Periductular | Thy1, NCAM | Bone marrow | Peri-bile ducts | Periportal injury (allyl acid) |
Oval cells | CD34, CD45, CD109, Thy-1, c-kit | Liver | Ductular | Centrolobular injury (acetylaminofluorene) |
Mesenchymal | CD13, CD29, CD44, CD54, CD90, CD105, CD166 | Bone marrow | Still needs proof | Unknown |
Liver cancer | CD133, EpCAM, ABCG2 | Unclear | Unclear | Oncogenic stimuli |