Table 2.

Selected genes and model proteins used for structure prediction. Bold ID of PDB indicates that the reference protein itself was detected in PDB.

Reference gene symbol	Model PDB ID	P-value	gene symbol
AIM2	3RN5_A	4 ×10−84	INTERFERON-INDUCIBLE PROTEIN AIM2
CARD15	3CIY_B	1 ×10−58	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE (TLR4)
CD82	2BG9_A	0.48	ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA CHAIN
CSF1R	3B43_A	5 ×10−58	TITIN
CSF3	1GNC_A	8 ×10−66	GRANULOCYTE COLONY-STIMULATING FACTOR
CSF3R	3DMK_A	4 ×10−64	DOWN SYNDROME CELL ADHESION MOLECULE (DSCAM)
DHCR24	2Q4W_A	1 ×10−114	CYTOKININ DEHYDROGENASE 7 (CKO7)
ERCC3	2W74_D	1 ×10−151	TYPE I RESTRICTION ENZYME ECOR124II R PROTEIN (HSDR)
GRB7	3HK0_B	3 ×10−73	GROWTH FACTOR RECEPTOR-BOUND PROTEIN 10 (GRB10)
HGF	4DUU_A	1 ×10−179	PLASMINOGEN
HOXB2	2D5V_A	1 ×10−23	HEPATOCYTE NUCLEAR FACTOR 6 (HNF-6)
IFNGR2	3T1W_A	4 ×10−43	FOUR-DOMAIN FIBRONECTIN FRAGMENT
LCN2	1X71_A	4 ×10−52	NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (NGAL)
LMO2	2XJY_A	2 ×10−33	RHOMBOTIN-2
LTB4R	2KS9_A	2 ×10−77	SUBSTANCE-P RECEPTOR
MMP14	1SU3_B	1 ×10−160	INTERSTITIAL COLLAGENASE (MMP-1)
MMP8	1SU3_B	1 ×10−171	INTERSTITIAL COLLAGENASE (MMP-1)
MPL	3L5H_A	8 ×10−61	INTERLEUKIN-6 RECEPTOR SUBUNIT BETA (IL6RB)
PADI4	2DEW_X	0.0	PROTEIN-ARGININE DEIMINASE TYPE IV
PECAM1	3DMK_A	1 ×10−104	DOWN SYNDROME CELL ADHESION MOLECULE (DSCAM)
PI3	1TWP_A	2 ×10−19	WHEY ACIDIC PROTEIN (WAP)
RARA	3DZY_A	4 ×10−95	RETINOIC ACID RECEPTOR RXR-ALPHA
S100A2	2RGI_A	4 ×10−19	PROTEIN S100-A2
SEPT9	3FTQ_A	1 ×10−137	SEPTIN-2
SLC22A18	1PW4_A	1 ×10−108	GLYCEROL-3-PHOSPHATE TRANSPORTER
SPI1	1GVJ_B	1 ×10−21	C-ETS-1 PROTEIN (ETS1)
SPP1	1D2T_A	1 ×10−12	ACID PHOSPHATASE (ACP)
STAT5A	1Y1U_A	0.0	SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION (STAT5A)
SYK	2OZO_A	1 ×10−170	TYROSINE-PROTEIN KINASE ZAP-70
TIE1	3DMK_A	2 ×10−88	DOWN SYNDROME CELL ADHESION MOLECULE (DSCAM)
TM7SF3	1AR1_A	6 ×10−88	CYTOCHROME C OXIDASE
TRIP6	1B8T_A	2 ×10−32	CYSTEINE-RICH PROTEIN 1 (CRP1)
VAMP8	2KOG_A	1 ×10−21	VESICLE-ASSOCIATED MEMBRANE PROTEIN 2 (VAMP2)