Table 1.
Wildtype | mnm1-1/2 | OE | ||||
---|---|---|---|---|---|---|
Metabolite | Avg | SE | Avg | SE | Avg | SE |
CENTRAL C/N METABOLITES | ||||||
Hydroxylamine | 10033 | 1392 | 14533* | 1077 | 11588 | 1167 |
Allantoin | 572 | 54 | 455* | 32 | 606 | 61 |
Arginine + ornithine | 1274 | 89 | 1602* | 108 | 1274 | 82 |
Pyruvic acid | 3083 | 490 | 5143* | 700 | 4294* | 683 |
Succinic acid | 3876 | 232 | 3651 | 237 | 4536* | 206 |
Glyceric acid | 11368 | 1309 | 17464* | 1664 | 15693* | 1441 |
Enolpyruvate | 433 | 41 | 658* | 76 | 546* | 64 |
SUGARS | ||||||
Rhamnose | 7290 | 626 | 8235* | 415 | 8394* | 523 |
Sophorose | 318 | 55 | 411* | 25 | 351 | 27 |
Glycero-guloheptose | 5660 | 692 | 6744* | 469 | 6433* | 505 |
N-acetyl-D-hexosamine | 3922 | 410 | 4078 | 184 | 4605* | 209 |
N-acetyl-D-mannosamine | 12471 | 1627 | 15666* | 1035 | 14475* | 1190 |
MISCELLANEOUS | ||||||
1-hexadecanol | 633 | 70 | 611 | 34 | 510* | 44 |
FAD | 194 | 26 | 254* | 19 | 217 | 19 |
Ferulic acid | 182 | 17 | 230* | 17 | 191 | 20 |
Average metabolite accumulation across the insertional (mnm1-1 and mnm1-2) and OE genotypes. A asterisk after the average (Avg) and standard error (SE) for either the mnm1-1/2 or OE genotypes indicates that the specific metabolites significantly differ across both alleles within either the mnm1-1/2 or OE genotypes with respect to WT in the nested ANOVA analysis. Each genotype was measured in 8 fold replication across two independent experiments (N = 8 for WT, N = 16 for mnm1, and N = 16 for OE). Unknown compounds are listed in Table S3.