Table 1.

List of clinical and imaging features used in the differential diagnosis between enchondroma and chondrosarcoma

Enchondroma	Chondrosarcoma
More common in extremities	More common in the axial skeleton
No pain (only if associated with fracture)	Can cause pain
No periostitis	Can have associated periostitis
No growth beyond skeletal maturity	Rapid growth, regardless of the skeletal maturity
No soft tissue component	Associated focal cortical thickening
Absence of bone oedema	Different patterns of signal intensity
Size usually ≤4 cm	Bone destruction
	Loss of calcifications on follow-up
	Soft tissue component
	Bone marrow oedema
	Size usually >4 cm