Table 1.

Insulin and proinsulin content in Con and ADCY5 shRNA-treated islets (n = 4 donors)

	Con	shRNA
Proinsulin content (ng/islet)	0.82 ± 0.11	0.93 ± 0.07
Insulin content (ng/islet)	32.8 ± 3.5	29.8 ± 3.1
Proinsulin:insulin (%)	2.6 ± 0.5	4.0 ± 1.2

Data are means ± SEM.