Figure 7.

Receiver operating characteristic curve using maximum nuclear size to classify low-grade (Grades I and II) and high-grade tumors (Grades III and IV). The optimal operation point is at a maximum nuclear size of 12.0 μm, which gives a false positive rate of 0.2 and a true positive rate of 1.0. The area under the curve is 0.97, suggesting good sensitivity and specificity using nuclear size in the image analysis algorithm to classify low-grade tumors from high-grade ones