Table 1. Characteristics of Liver Transplant Recipients and Donors (2003-2009) With Comparisons by HHI Levels.
Characteristic | Total Population (n = 38,385) |
HHI Level | Comparison of HHI Levels: P Value | Trend: P Value |
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No Competition (n = 6613) |
Low Competition (n = 10,316) |
Mid Competition (n = 11,346) |
High Competition (n = 10,110) |
No Versus Low |
No Versus Mid |
No Versus High |
Low Versus Mid |
Low Versus High |
Mid Versus High |
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Recipients | ||||||||||||
Match MELD score (%) | ||||||||||||
Status 1/1a/1b | 5.4 | 3.9 | 4.9 | 5.9 | 6.4 | 0.003 | <0.001 | <0.001 | 0.001 | <0.001 | 0.12 | <0.001 |
6-10 | 2.0 | 2.1 | 2.7 | 1.0 | 2.4 | 0.10 | <0.001 | 0.19 | <0.001 | 0.14 | <0.001 | 0.16 |
11-20 | 23.7 | 39.1 | 28.4 | 19.4 | 13.6 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
21-30 | 49.8 | 44.8 | 49.2 | 53.6 | 49.3 | <0.001 | <0.001 | <0.001 | <0.001 | 0.90 | <0.001 | <0.001 |
31-40 | 19.1 | 10.0 | 14.8 | 20.1 | 28.2 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Other | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.75 | 0.90 | 0.12 | 0.62 | 0.03 | 0.06 | 0.02 |
Active exception (%) | ||||||||||||
No exception | 72.5 | 78.2 | 76.2 | 70.7 | 67.1 | 0.003 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Yes, non-HCC | 7.6 | 4.4 | 5.9 | 9.6 | 9.0 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.15 | <0.001 |
Yes, HCC | 19.9 | 17.3 | 17.9 | 19.7 | 23.9 | 0.37 | <0.001 | <0.001 | 0.001 | <0.001 | <0.001 | <0.001 |
Abdominal surgery (%) | 41.8 | 47.6 | 44.4 | 41.8 | 35.3 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Life support (%) | 7.0 | 4.4 | 6.5 | 8.7 | 7.2 | <0.001 | <0.001 | <0.001 | <0.001 | 0.05 | <0.001 | <0.001 |
Dialysis (%) | 9.9 | 6.3 | 8.3 | 11.4 | 12.2 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.06 | <0.001 |
Previous transplant (%) | 8.0 | 6.5 | 8.7 | 8.2 | 7.9 | <0.001 | <0.001 | 0.001 | 0.20 | 0.04 | 0.39 | 0.05 |
Functional status (%) | ||||||||||||
No assistance | 46.8 | 49.6 | 48.9 | 46.1 | 43.8 | 0.32 | <0.001 | <0.001 | <0.001 | <0.001 | 0.001 | <0.001 |
Some assistance | 24.1 | 24.9 | 27.6 | 24.9 | 19.1 | <0.001 | 0.93 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Total assistance | 16.5 | 9.4 | 14.9 | 17.1 | 21.9 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Missing | 12.6 | 16.0 | 8.6 | 11.9 | 15.1 | <0.001 | <0.001 | 0.11 | <0.001 | <0.001 | <0.001 | 0.002 |
Donors | ||||||||||||
Age (%) | ||||||||||||
<40 years | 45.2 | 48.8 | 44.5 | 47.7 | 40.8 | <0.001 | 0.16 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
40-49 years | 20.0 | 20.5 | 19.1 | 20.6 | 19.8 | 0.03 | 0.90 | 0.30 | 0.008 | 0.21 | 0.18 | 0.96 |
50-59 years | 19.1 | 19.0 | 19.1 | 18.6 | 19.6 | 0.87 | 0.44 | 0.32 | 0.29 | 0.35 | 0.44 | 0.46 |
60-69 years | 10.8 | 9.4 | 11.3 | 10.0 | 12.0 | <0.001 | 0.16 | <0.001 | 0.003 | 0.13 | <0.001 | <0.001 |
>70 years | 5.0 | 2.3 | 6.0 | 3.2 | 7.8 | <0.001 | 0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Race (%) | ||||||||||||
White | 67.9 | 77.7 | 65.3 | 68.5 | 63.6 | <0.001 | <0.001 | <0.001 | <0.001 | 0.01 | <0.001 | <0.001 |
Black | 15.7 | 11.0 | 16.5 | 16.2 | 17.5 | <0.001 | <0.001 | <0.001 | 0.59 | 0.04 | 0.009 | <0.001 |
Hispanic | 13.0 | 7.5 | 15.9 | 11.9 | 14.9 | <0.001 | <0.001 | <0.001 | <0.001 | 0.06 | <0.001 | <0.001 |
Asian | 2.3 | 2.0 | 1.4 | 2.5 | 3.0 | 0.003 | 0.06 | <0.001 | <0.001 | <0.001 | 0.02 | <0.001 |
Other | 1.1 | 1.8 | 0.9 | 0.9 | 1.0 | <0.001 | <0.001 | <0.001 | 0.98 | 0.83 | 0.84 | <0.001 |
Desmopressin (%) | 26.0 | 33.9 | 26.3 | 21.6 | 25.3 | <0.001 | <0.001 | <0.001 | <0.001 | 0.10 | <0.001 | <0.001 |
Partial/split liver (%) | 1.4 | 0.7 | 1.1 | 1.4 | 2.1 | 0.01 | <0.001 | <0.001 | 0.02 | <0.001 | <0.001 | <0.001 |
Cold ischemia time (%) | ||||||||||||
<9 hours | 67.9 | 72.0 | 71.1 | 67.9 | 61.7 | 0.22 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
9-11.9 hours | 17.2 | 17.9 | 18.3 | 13.4 | 19.8 | 0.46 | <0.001 | 0.003 | <0.001 | 0.009 | <0.001 | 0.52 |
>12 hours | 6.5 | 4.8 | 7.2 | 5.1 | 8.6 | <0.001 | 0.39 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Missing | 8.4 | 5.3 | 3.4 | 13.5 | 10.0 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Share type (%) | ||||||||||||
Local | 70.8 | 78.6 | 63.8 | 71.8 | 71.6 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.71 | 0.01 |
Regional | 22.9 | 17.4 | 29.7 | 26.2 | 15.9 | <0.001 | <0.001 | 0.02 | <0.001 | <0.001 | <0.001 | <0.001 |
National | 6.3 | 4.1 | 6.4 | 1.9 | 12.5 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
DRI quartiles (%) | ||||||||||||
1 (<1.12) | 25.4 | 33.3 | 22.7 | 27.9 | 20.4 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
2 (>1.12-1.37) | 24.7 | 24.6 | 24.3 | 26.9 | 22.8 | 0.62 | 0.001 | 0.006 | <0.001 | 0.01 | <0.001 | 0.10 |
3 (>1.37-1.68) | 24.9 | 23.8 | 25.4 | 24.9 | 25.2 | 0.02 | 0.09 | 0.04 | 0.40 | 0.66 | 0.69 | 0.17 |
4 (>1.68) | 24.9 | 18.3 | 27.6 | 20.4 | 31.7 | <0.001 | 0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
MELD score of 31-40 and DRI > 1.68 (%) | 3.6 | 1.8 | 2.8 | 3.2 | 6.2 | <0.001 | 0.001 | <0.001 | 0.05 | <0.001 | <0.001 | <0.001 |
Days on wait list* | 63 (14-230) | 46 (12-153) | 49 (13-175) | 69 (14-267) | 98 (18-306) | 0.02 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Albumin (g/dL)* | 2.9 (2.4-3.4) | 2.8 (2.4-3.3) | 3.0 (2.5-3.4) | 2.9 (2.4-3.4) | 2.9 (2.4-3.4) | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.35 | 0.03 |
Creatinine* | 1.1 (0.8-1.7) | 1.1 (0.8-1.5) | 1.1 (0.8-1.6) | 1.16 (0.8-1.8) | 1.18 (0.8-2.0) | 0.86 | <0.001 | <0.001 | <0.001 | <0.001 | 0.12 | <0.001 |
Donor height (cm)* | 173 (165-180) | 173 (165-180) | 173 (165-180) | 173 (165-180) | 171 (165-178) | <0.001 | 0.005 | <0.001 | 0.05 | <0.001 | <0.001 | <0.001 |
Length of stay (days)* | 10 (7-18) | 9 (7-15) | 10 (7-18) | 11 (7-19) | 10 (7-19) | <0.001 | <0.001 | <0.001 | <0.001 | 0.03 | 0.005 | <0.001 |
NOTE: Some groups of percentages do not add up to exactly 100 because of rounding. To account for multiple comparisons, only P < 0.008 was considered statistically significant.
The data are presented as medians and interquartile ranges.