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. 2014 Aug 25;21:41. doi: 10.1051/parasite/2014043

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© D. Stark et al., published by EDP Sciences, 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Full alignment of beta-tubulin amino acid sequences from D. fragilis with tubulin sequences derived from Trichomonads and other eukaryotes. The residues highlighted blue are those thought to be predictors of albendazole susceptibility in protozoa as described in previous studies. Amino acids shaded yellow represent the most common amino acid at that position (predicted consensus based on this alignment). Amino acids shaded orange are those which differ from the predicted consensus. Note however that at positions 8, 430, 434 and 446, a consensus cannot be resolved. TV: Trichomonas vaginalis, DF: Dientamoeba fragilis, HM: Histomonas meleagridis, TF: Tritrichomonas foetus, HS: Homo sapiens, DR: Danio rerio. For Histomonas meleagridis and Trichomonas vaginalis the species acronym is followed by the corresponding UniprotKB identifier. For all other organisms, the species acronym is followed by the corresponding Genbank accession number.