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. Author manuscript; available in PMC: 2014 Aug 22.
Published in final edited form as: Nature. 2013 Oct 24;502(7472):550–554. doi: 10.1038/nature12710

Figure 1. Hepatic PPARδ and Acc1 are linked to muscle FA utilization.

Figure 1

a. Serum TG and FFA levels in adGFP or adPPARδ mice (n=5). b. Ex vivo fatty acid uptake and oxidation in isolated soleus muscle. c. Hepatic TG and serum TG and FFA levels in LACC1KD or control (Scramble) mice (n=5). Inset: Immunoblotting of liver Acc protein. d. Ex vivo fatty acid uptake in isolated soleus muscle. e. In vivo fatty acid uptake in soleus and gastrocnemius muscle. f. Serum 3H-oleic acid disappearance. Inset: 3H-FA clearance. AUC: area under the curve of disappearance. *p<0.05 (t-test), data shown as mean±SEM.