Table 4.
Framingham 10-year coronary heart disease (CHD) and stroke risk scores for individuals with refractory hypertension, resistant hypertension and treated hypertension.
| Characteristic | Refractory | Resistant | Treated |
|---|---|---|---|
| 10-year CHD risk* | 17.5 (10.0 – 26.0) | 11.7 (6.4 – 19.7) | 7.9 (4.2 – 14.3) |
| Difference in 10-year CHD risk† | |||
| Refractory vs. resistant hypertension | Reference | 4.0(0.8–7.2)‡ | |
| Refractory vs. all treated hypertension | Reference | 7.0 (4.6 – 9.5)§ | |
| 10-year stroke risk† | 20.8 (12.9 – 31.3) | 16.2 (9.2 – 26.8) | 9.5 (5.3 – 17.0) |
| Difference in 10-year stroke risk† | |||
| Refractory vs. resistant hypertension | Reference | 5.1 (1.8 – 8.5)∥ | |
| Refractory vs. all treated hypertension | Reference | 8.1 (5.9 – 10.3)§ | |
Individuals with prevalent CHD at baseline were excluded from the 10-year CHD risk calculation. Individuals with prevalent stroke at baseline were excluded from the 10-year CHD risk calculation.
Median (25% - 75%).
Numbers reported are difference in median (95% confidence interval) 10-year risk after adjustment for age, race, sex, and geographic region of residence.
p-value < 0.014
p-value < 0.001
p-value < 0.003