Table 2. Prevalence of transmitted HIV drug resistance according to the SDRM mutation list and of acquired HIV drug resistance according to the IAS mutation list.
Transmitted HIV drug resistance | n (%) | (95% CI) | Beta | OR (95% CI) | p for trend |
First Prot/RT sequence from naive patients | Prevalence of DRMs according to SDRM mutation list (Bennett D. et al. 2009) | ||||
Total | 1950 (100.0%) | p (2001–2011) | |||
DRMs | 203 (10.4%) | (9.1–11.8) | −0.018 | 0.98 (0.92–1.04) | 0.561 |
NRTI mutations | 128 (6.6%) | (5.5–7.8) | −0.016 | 0.98 (0.91–1.06) | 0.667 |
TA mutations | 89 (4.6%) | (3.7–5.6) | 0.002 | 1.00 (0.92–1.10) | 0.972 |
T215revertants | 56 (2.9%) | (2.2–3.7) | 0.058 | 1.06 (0.94–1.19) | 0.337 |
NNRTI resistance | 61 (3.1%) | (2.4–4.0) | −0.031 | 0.97 (0.87–1.08) | 0.560 |
PI resistance | 56 (2.9%) | (2.2–3.7) | −0.020 | 0.98 (0.88–1.10) | 0.723 |
Single/multi drug class resistance | 203 (10.4%) | ||||
One class resistance | 169 (8.7%) | (7.5–10.0) | |||
Two classes resistance | 26 (1.3%) | (0.9–1.9) | |||
Three classes resistance | 8 (0.4%) | (0.2–0.8) |
Highly significant results are marked in bold fonts.