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. 2014 Aug 22;9(8):e105950. doi: 10.1371/journal.pone.0105950

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© 2014 Cosgrove et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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NK cells were identified in the blood and liver of groups of HCV-infected and -uninfected individuals by flow cytometry using a robust gating strategy (A). The size of the NK and T cell populations as a percentage of the total lymphocyte population, as well as the T:NK cell ratio was calculated in the liver and blood in HCV-infected and -uninfected individuals (B), as was the contribution of the CD56^bright and CD56^dim NK cell subsets to the total NK cell population (C). Statistical significance was accepted at p<0.05 and is indicated by * (p<0.05), ** (p<0.01) and *** (p<0.001).