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. 2014 Aug 22;9(8):e105950. doi: 10.1371/journal.pone.0105950

Figure 3. Tissue- and disease-specific differences in NK cell functionality.

Figure 3

Functional responses of liver-resident and blood NK cells were assessed in groups of HCV-infected and –uninfected individuals. NK cell degranulation (CD107a) and cytokine production (MIP1β and IFNγ) were measured by flow cytometry in the absence (A) or presence (B) of K562 cells (NKG2D ligation), 721.221 cells (NCR ligation) or antibody-coated p815 cells (ADCC-mediated stimulation). Statistical significance was accepted at p<0.05 and is indicated by * (p<0.05), ** (p<0.01), *** (p<0.001) and **** (p<0.0001).