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. Author manuscript; available in PMC: 2014 Aug 22.
Published in final edited form as: Aging Cell. 2013 Jan 10;12(2):177–183. doi: 10.1111/acel.12036

Figure 5. Spontaneous tumor incidence in p66KO mice.

Figure 5

Tumor frequencies in 129Sv and C57/Bl6J backgrounds as indicated WT (Black bars) and p66KO (white bars): i) euthanized 1-year old mice (n=50 per strain) (p > 0.5 for both strain or p66Shc mutation effects) ii) mice that died spontaneously within one year of age (<1year; n=100 and n=80 for the 129Sv and C57Bl6J backgrounds respectively; p = 0.6212 for the effect of p66Shc mutation in 129Sv background); iii) mice that died spontaneously, regardless of their age [n (number of mice observed) =180 and n= 190, 129Sv and C57Bl6/J WT respectively and n= 270 and n= 290, 129Sv and C57Bl/6J p66KO, collected over a period of 8 years; p= 0.5631 for the effect of p66Shc mutation in 129Sv background and p = 0.5467 for the effect of p66Shc mutation in C57Bl/6J background].