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. 2014 Aug 15;38(9):1274–1281. doi: 10.1097/PAS.0000000000000236

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Copyright © 2014 by Lippincott Williams & Wilkins

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivitives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/3.0.

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Immunohistochemical findings in SMARCB1-negative sinonasal carcinomas. A, Pancytokeratin (KL-1) was expressed in almost all tumor cells in all cases and showed diffuse or punctate perinuclear cytoplasmic pattern. B, Vimentin expression varied from diffuse (right) to partial/hybrid pattern (left). Note characteristic paranuclear dot-like pattern highlighting rhabdoid cells. C, CK5 showed an inverse pattern compared with that of vimentin indicating a dual population of CK5⁺/vimentin⁻ (basaloid) and CK5⁻/vimentin⁺ (rhabdoid) cells. D, Complete loss of nuclear SMARCB1/INI1 expression (case 1, note strong staining in inflammatory and endothelial cells).