Table 4.
Differences in regional fractional anisotropy (cluster corrected with voxel threshold t > 2.0).
| Comparison of groups | Cluster size |
Coordinates |
p value | ||
|---|---|---|---|---|---|
| x | y | z | |||
| NPSLE < HC | |||||
| 1683 | 24 | 26 | 2 | 0.001 | |
| 1382 | –24 | 31 | 5 | 0.002 | |
| Non-NPSLE < HC | |||||
| 536 | –6 | 26 | –1 | 0.027 | |
| NPSLE < non-NPSLE | |||||
| − | − | − | − | − | |
HC = healthy control, NPSLE = neuropsychiatric systemic lupus erythematosus; non-NPSLE = systemic lupus erythematosus without neuropsychiatric symptoms. In a first step voxels were thresholded at t > 2.0; permutation-based cluster statistics were then computed to obtain a multiple comparison corrected p values for each cluster. Coordinates refer to voxels with largest t values within a cluster.