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. 2014 Aug 15;9(1):396. doi: 10.1186/1556-276X-9-396

Figure 4.

Figure 4

Estrogenic disruption in the ER Calux assay with T47Dluc cells. Estrogenic activity given as luciferase induction relative to solvent control (=1, dashed line) in the ER Calux assay plated in 96-well plates. T47Dluc cells were treated with CNT (A), TCC (B), and mixture of both (CNT + 0.5% TCC (C), 1.56 mg CNT/L + 7.80 μg TCC/L to 25 mg CNT/L + 125 μg TCC/L; CNT + 1% TCC (D), 1.56 mg CNT/L + 15.60 μg TCC/L to 25 mg CNT/L + 250 μg TCC/L). Dots represent means of two independent exposure experiments with three internal replicates each. Error bars, standard deviation; *statistically significant from the EtOH control in repeated measures ANOVA on Ranks with Dunn's post hoc and p < 0.05.