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Vaginal delivery of lipoplexes in the estrus phase mouse vagina (Untreated), which is more reminiscent of the structure of the human vagina, was minimal and restricted to tissue debris in the lumen, unless the epithelium was pretreated with 5% citric acid (Treated). The scale bars present 200 μm in the top three panels and 20 μm in the bottom panel. Propidium idodide (PI) was used to stain the epithelium. Adapted with permission from (62).
