Table 1.

Time Course of the Plasma Concentrations of Progesterone and Corticosterone Following Ethanol (EtOH) Administration in C57BL/6J and DBA/2J Mice

	Progesterone		Corticosterone
	C57BL/6J	DBA/2J	C57BL/6J	DBA/2J
Saline	1.84 ± 0.54	0.37 ± 0.08	50.9 ± 6.97	34.4 ± 6.95
15 min	5.71 ± 0.62**	1.80 ± 0.42#	174.3 ± 8.87**	127.8 ± 9.35**
30 min	5.04 ± 0.79*	1.77 ± 0.55#	194.6 ± 11.27**	183.5 ± 9.39**
60 min	6.08 ± 1.21**	2.74 ± 0.14#	248.6 ± 12.32**	289.3 ± 14.06**
120 min	3.81 ± 1.06	1.78 ± 0.35	174.5 ± 19.70**	225.7 ± 13.74**

Mice were injected with EtOH (2 g/kg, i.p.) at the indicated times before euthanasia. Control mice received an equivalent volume of saline and were euthanized 60 minutes later. Levels are expressed as nanograms of steroid per milliliter of plasma and are average ± SEM of values from 9 C57BLV6J mice per group and from 8 DBA/2J mice per group with the exception of the saline-treated group for progesterone levels where n = 5.

^*p < 0.01

^**p < 0.001 vs the respective saline-treated group

^#p < 0.01 vs the respective EtOH-treated groups across strains; 2-way ANOVA followed by Bonferroni post hoc test.