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. 2014 Aug 7;2014:545038. doi: 10.1155/2014/545038

Table 2.

Effect of the compounds on intracellular amastigotes of L. amazonensis and selectivity index.

Samples Macrophages CC50 (µg/mL)  
(95% C.I.)a
Amastigotes CC50 (µg/mL)
(95% C.I.)a
Selectivity
index (SI)b
Methanolic extract 35.9 (±0.06) 8.1 (5.8–11.2) 4.4
Hexane 22.1 (±1.4) 6.9 (4.0–11.8) 3.2

aData are IC50 values in μg/mL and 95% confidence intervals are in brackets. bSelectivity index (SI) was calculated by dividing the CC50 of macrophages by the IC50 values of amastigotes of L. amazonensis.