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. Author manuscript; available in PMC: 2015 Jan 3.
Published in final edited form as: Nature. 2014 May 21;511(7507):94–98. doi: 10.1038/nature13297

Extended Data Figure 10. Model for the expanded roles of IDE in glucose homeostasis and gastric emptying based on the results of this study.

Extended Data Figure 10

IDE inhibition increases the abundance and signalling of three key pancreatic peptidic hormones—insulin, amylin and glucagon—with the corresponding physiological effects shown in blue, blue and red, respectively.