Table 4.

Integrin outside-in signaling.

Gene	SKBR3b	SUM190b	SUM149b	SKBR3c	SUM190c	SUM149c	Ratio 149/190d	GRB2 interact	Novoseek tomor hits
FN1e	0	0	1	1.3	0.1	111.9	6.6	+	159
FLNAe	420	5	524	7.0	12.6	414.3	4.9	+	9
ACTN1e	75	54	154	8.9	8.6	81.9	3.1	+	5
SRCf				7.2	0.1	7.5	3.0	+	397
ACTN4e	158	52	103	73.7	11.4	71.2	2.5	+	14
ACTB	499	545	476	1083.8	196.1	559.5	1.5	+	3
VCLe	100	5	17	8.6	3.1	8.9	1.3		28
ITGB1e	0	0	7	7.6	12.9	32.1	1.3	+	71
TLN1e	72	0	46	5.3	5.5	12.9	1.1		0
CTNNB1	0	12	12	8.4	21.9	49.0	1.1	+	1681
ITGA2e	0	0	6	0.2	2.4	3.7	0.4		28
GRB2f				10.2	7.7	10.0	0.3	+	35
VTN	2	0	0	2.5	0.0	0.1	0.1		102
ITGAV	2	0	0	1.3	7.1	7.9	0.1		23
ACTR3	28	16	17	15.6	20.4	20.8	0.0	+	5
MAP2K1e	0	2	0	3.1	10.3	7.8	−0.4	+	45
RAC1	15	14	12	190.8	23.0	12.0	−0.9	+	88

^aThis pathway is retrieve from GeneGo in January, 2012.

^bSpectral counts

^cRPKM values

^dRPKM values are used to show the expression differences in two IBC cell lines, and the values in the ratio column are calculated as followed: $\mathit{\text{Ratio}}\left(\frac{149}{190}\right)={\mathit{log}}_2^{\frac{\mathit{\text{RPKM SUM}}149+1}{\mathit{\text{RPKM SUM}}190+1}}$.

^eProteins with higher expression in SUM149 are highlighted in yellow and in blue those with higher levels in SUM190.

^fKnown oncogene.