Table 2.
Baseline characteristics of study participants by number of copies of the APOE ε4 allele
| Characteristics | APOE ε4 allele | ||
|---|---|---|---|
| Mean (SD) or N (%) | |||
| 0 N =2745 | 1-2 N=1405 | p-valuea | |
| Age | 71.9 (5.9) | 71.0 (5.4) | <.001 |
| Education | 12.5 (3.5) | 12.6 (3.4) | .45 |
| Women | 1747 (64%) | 866 (62%) | .20 |
| African Americans | 1,820 (66%) | 1,077 (76%) | <.001 |
| Body mass index | 28.4 (5.9) | 28.8 (6.0) | .031 |
| Chronic health conditions | 0.96 (.87) | 0.97 (.88) | .92 |
| Stroke | 192 (7%) | 118 (8%) | .10 |
| MI1 | 311 (11%) | 128 (9%) | .021 |
| Hypertension | 1414 (52%) | 746 (53%) | .32 |
| Diabetes | 195(7%) | 90 (6%) | .40 |
| Cancer | 469 (17%) | 243 (17%) | .86 |
| Hip fracture | 62 (2%) | 32 (2%) | .96 |
| Cognitive function | 0.3885 (.6332) | 0.3467 (.6575) | .047 |
| Symbol digits | 32.3 (12.8) | 31.6 (13.0) | .12 |
| Delayed recall | 8.6 (2.6) | 8.5 (2.4) | .083 |
| Immediate recall | 9.1 (2.2) | 9.0 (2.1) | .11 |
| MMSE2 | 27.3 (3.6) | 26.5 (3.7) | .081 |
| Depressive symptoms | 1.4 (1.8) | 1.5 (1.9) | .67 |
1
Myocardial Infarction
2
Mini-mental state examination
a
p-value is based on t-test for continuous or chi-square test for discrete measures