Table 2.
Percentage yield, drug loading %, drug encapsulation efficiency %, mean particle size, density, floating lag time and floating % after 8 h of KT floating beads.
| Formulae code | Yield (%) | Drug loading (%) | Drug encapsulation efficiency (%) | Mean particle size (μm) | Floating lag time (s) | Floating (%) after 8 (h) |
|---|---|---|---|---|---|---|
| Physicochemical characterization | ||||||
| F1 | 80.0 ± 4.0 | 56.9 ± 3.6 | 45.00 ± 1.7 | 711 ± 14.50 | 41.0 ± 1.70 | 95 ± 5.60 |
| F2 | 84.5 ± 2.3 | 88.5 ± 4.8 | 70.25 ± 2.1 | 825 ± 19.90 | 86.0 ± 4.40 | 92.5 ± 6.8 |
| F3 | 86.5 ± 2.0 | 73.2 ± 6.3 | 73.25 ± 2.0 | 907 ± 17.00 | 95.0 ± 6.00 | 90.4 ± 7.6 |
| F4 | 87.0 ± 2.6 | 86.1 ± 5.9 | 85.50 ± 1.5 | 1005 ± 22.9 | 120 ± 10.5 | 91 ± 6.60 |
| F5 | 83.5 ± 2.5 | 78.5 ± 3.6 | 64.25 ± 2.1 | 860 ± 25.00 | 90.0 ± 5.60 | 93.6 ± 2.5 |
| F6 | 84.0 ± 3.6 | 82.3 ± 7.1 | 67.50 ± 1.5 | 975 ± 22.90 | 110 ± 9.50 | 91.2 ± 2.3 |
| F7 | 85.0 ± 1.7 | 82.3 ± 6.5 | 69.00 ± 1.7 | 1112 ± 13.1 | 140 ± 12.5 | 92.1 ± 3.5 |
| F8 | 89.0 ± 2.7 | 88.5 ± 3.6 | 78.00 ± 1.8 | 1000 ± 21.8 | 83.0 ± 6.10 | 88.5 ± 4.0 |
| F9 | 90.0 ± 3.6 | 90.0 ± 5.7 | 80.00 ± 1.0 | 1130 ± 13.2 | 95.0 ± 7.0 | 86 ± 4.00 |
| F10 | 94.5 ± 1.5 | 92.3 ± 4.4 | 86.75 ± 3.2 | 1260 ± 22.7 | 125 ± 9.5 | 86.5 ± 2.9 |
| F11 | 81.0 ± 2.0 | 73.1 ± 3.2 | 58.25 ± 1.1 | 710 ± 18.00 | 45.0 ± 4.40 | 96 ± 1.00 |
| F12 | 82.5 ± 1.5 | 74.6 ± 4.8 | 61.00 ± 1.0 | 780 ± 31.20 | 53.0 ± 4.40 | 95.5 ± 2.5 |
| F13 | 83.0 ± 2.5 | 77.0 ± 3.1 | 63.25 ± 1.2 | 801 ± 18.40 | 50.0 ± 2.00 | 95 ± 2.00 |
All values are mean ± SD of three determinations.