Table 5.
Parameters of analgesic effect of KT solution, Ketoral® tablets and KT floating beads (F10) in mice using hot plate and tail flick methods.
| KT in | Parameters of analgesic effect using hot plate method |
Parameters of analgesic effect using tail flick method |
||||
|---|---|---|---|---|---|---|
| MR (s) ± SE | TMR (h) | DA (h) | MR (s) ± SE | TMR (h) | DA (h) | |
| Solution | 12.6 ± 0.55 | 2 | 5 | 8.2 ± 0.31 | 2 | 4 |
| Ketoral® | 13.0 ± 0.37 | 4 | 5 | 8.4 ± 0.14 | 3 | 6 |
| F10 (fast) | 9.80 ± 0.67 | 4 | 6 | 7.5 ± 0.15 | 4 | 7 |
| F10 (fed) | 11.5 ± 0.67 | 4 | >8 | 7.9 ± 0.10 | 4 | >8 |
All values are means ± SE of six determinations. MR is the maximum analgesic response, TMR is the time of maximum analgesic response and DA is the duration of analgesic action.