Table 1.

Enzymatic activities in tissues and erythrocytes of rats after 72 h from ip administration of ADT (10 mg/kg/day for three days). Control animals were administered with vehicle (DMSO) only. Data are expressed as mean ±SD (n=4 for each treatment).

Treatment	RBCs	Liver	Kidney	Lung	Heart	Testis	Brain
	CBS1 (mU/mg protein)
ADT	0	0.094±0.007	0.037±0.005	0	0	0	0.017±0.004
Vehicle	0	0.087±0.005	0.032±0.006	0	0	0	0.021±0.005
	γ–GCS (mU/mg protein)
ADT	0.785±0.037	38.0±8.2	45.4±2.6	5.94±0.37	5.84±0.86	13.1±2.8	18.7±1.6
Vehicle	0.723±0.148	33.7±6.5	42.6±4.3	6.48±0.53	4.90±0.57	11.7±4.6	16.6±3.0
	GR (mU/mg protein)
ADT	1.21±0.37	54.5±6.85	213±35	64.9±10.4	27.3±5.4	19.7±1.0	13.2±2.2
Vehicle	1.08±0.23	43.8±9.58	237±47	70.6±8.3	24.0±3.3	22.8±3.8	11.6±3.8
	GST (mU/mg protein)
ADT	3.12±0.59	659±96	141±18	68.1±5.94	72.7±5.2	541±73	23.7±4.5
Vehicle	2.84±0.45	587±64	137±9	64.2±6.66	69.2±4.4	604±87	26.1±3.8

¹Abbreviations: CBS: cystathionine-β-synthase; γ–GCS; γ-glutamyl-cysteine synthase; GR: glutathione reductase; GST: glutathione transferase