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. Author manuscript; available in PMC: 2014 Aug 25.
Published in final edited form as: Cold Spring Harb Protoc. 2014 Apr 1;2014(4):339–349. doi: 10.1101/pdb.top069807

TABLE 1.

Cre, FLP, and Dre recognition sites: classical and variant sites

Recombinase Recognition Site Inverted Repeat 1 Spacer Inverted Repeat 2
Cre loxP ATAACTTCGTATA ATGTATGC TATACGAAGTTAT
Cre lox2272 ATAACTTCGTATA ATGTGTAC TATACGAAGTTAT
Cre lox511 ATAACTTCGTATA ATGTATAC TATACGAAGTTAT
Cre lox m2 ATAACTTCGTATA AGAAACCA TATACGAAGTTAT
Cre lox66 ATAACTTCGTATA ATGTATGC TATACGAACGGTA
Cre lox71 TACCGTTCGTATA ATGTATGC TATACGAAGTTAT
Cre lox72 TACCGTTCGTATA ATGTATGC TATACGAACGGTA
FLP FRT GAAGTTCCTATTC TCTAGAAA GTATAGGAACTTC
FLP F3 GAAGTTCCTATTC TTCAAATA GTATAGGAACTTC
FLP F5 GAAGTTCCTATTC TTCAAAAG GTATAGGAACTTC
Dre rox TAACTTTAAATAAT GCCA ATTATTAAAGTTA

Nucleotides, in the variant sites, that have been altered from the classical sites are underlined.