Table 1.
Demographic and clinical characteristics of study participants
| OCD patients (n = 23) | Healthy controls (n = 20) | Test statistic | p value | |
|---|---|---|---|---|
| Age (years) | 30.9 (8.8) | 32.6 (10.0) | t(41) = 0.60 | 0.6 |
| Sex, M:F | 11:12 | 11:9 | Χ2(1) = 0.22 | 0.7 |
| Ethnicity | 16 Cau/4 His/3 AA | 14 Cau/3 His/2 AA/1 Un | Χ2(3) = 1.27 | 0.7 |
| FS‐IQ | 107.1 (27.3) | 118.2 (8.6) | t(41) = 1.9 | 0.1 |
| Age of OCD onset, years | 16.1 (7.5) | |||
| History of treatment with psychotropic | 11a | |||
| SRI | 9 | |||
| SNRI | 1 | |||
| Duration off psychotropic medication, before MRI Scan (in weeks) | 94 (64) | |||
| DSM‐IV Axis I comorbidity | ||||
| No current or past comorbidities | 17 | |||
| Specific phobia | 1 | |||
| Specific phobia, alcohol abuse, generalized anxiety disorder, and history of MDD | 1 | |||
| Binge eating disorder, social phobia, and history of MDD | 1 | |||
| History of MDD | 3 | |||
| Y‐BOCS | 25.9 (4.2) | |||
| HAM‐D | 4.6 (3.5) |
Note:AA, African American; Cau, Caucasian; His, Hispanic; OCD, Obsessive‐Compulsive Disorder; FS‐IQ, Full Scale Intelligence Quotient; MDD, Major Depressive Disorder; GAD, Generalized Anxiety Disorder; HAM‐D, Hamilton Depression Scale; Y‐BOCS, Yale‐Brown Obsessive Compulsive Scale; SRI, Serotonin reuptake inhibitor, SNRI, Serotonin norepinephrine reuptake inhibitor; Un, Unspecified. Values are mean (SD) unless specified.
a
One participant could not recall the specific psychotropic taken.
b