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Additional Guidelines in UCSF Down-Staging Protocol
A minimum follow-up period of 3 months after down-staging is required before deceased donor liver transplantation (DDLT) or LDLT, along with imaging studies meeting the above defined criteria for successful down-staging.
Approval by the regional UNOS review board for priority listing is needed for DDLT after successful down-staging.
Patients can undergo LDLT if a donor is available, and if imaging studies meet proposed UCSF expanded criteria.10
Those with acute hepatic decompensation after down-staging procedures are not eligible for DDLT or LDLT unless they meet the above criteria.
In patients treated with resection as a down-staging procedure, the presence of microvascular tumor invasion in the resection specimen is a contraindication to DDLT or LDLT.