Table 8.
Comparison of Clinical Characteristics of 35 Liver Transplantation Patients and 18 Patients with Treatment Failure
| Characteristics | Transplantation (n = 35) |
Treatment Failure (n = 18) |
|---|---|---|
| Median age, years | 58.2 | 59.5 |
| Sex (M/F) | 29/6 | 14/4 |
| Asian, n (%) | 13 (37.1) | 4 (22.2) |
| Child class cirrhosis (A/B/C) | 15/16/4 | 8/8/2 |
| Cause of liver disease, n (%) | ||
| Hepatitis C virus | 24 (68.6) | 9 (50.0) |
| Hepatitis B virus | 15 (25.0) | 6 (33.3) |
| Other | 4 (11.4) | 3 (16.7) |
| Median AFP, ng/mL (range)* | 12.9 (2.1–760) | 271.9 (5.3–58,096) |
| HCC characteristics before down-staging, n (%) | ||
| One lesion | 11 (31.4) | 9 (25.7) |
| Two lesions | 14 (40.0) | 5 (27.8) |
| Three lesions | 7 (20.0) | 3 (16.7) |
| Four or five lesions | 3 (8.6) | 1 (5.6) |
*
The difference in the median AFP level within 3 months prior to OLT and the median AFP within 3 months before treatment failure was statistically significant (P = 0.001; Mann-Whitney U test). None of the other characteristics are statistically different between the two groups.