Table 1. No effect of topiramate on the day of treatment on food and water intake in P rats under the two-bottle choice procedure and Wistar rats tested under the two- and three-bottle choice procedure.
Strain/group | Treatment | Food (mean ± SE) | Water (mean ± SE) |
---|---|---|---|
P rats | Vehicle | 2.67±4.88 | 10.63±8.04 |
5 mg/kg | −4.54±5.55 | −2.91±7.81 | |
10 mg/kg | −4.02±6.88 | 15.15±9.38 | |
Wistar rats (two-bottle choice) | Vehicle | −1.85±1.44 | 3.79±8.99 |
5 mg/kg | 0.13±1.13 | −3.93±5.81 | |
10 mg/kg | 0.95±1.85 | 4.88±9.71 | |
Wistar rats (three-bottle choice) | Vehicle | 1.58%±2.09 | −9.94±6.08 |
5 mg/kg | −1.30%±1.30 | 4.30±4.98 | |
10 mg/kg | −0.42%±0.42 | −5.12±3.29 |