Table 1.
Baseline histology | Patient-years of follow-up |
Incident EAC cases, n |
EAC incidence rate per 1000 person-years, [95%CI] |
Deaths from EAC, n |
EAC mortality rate per 1000 person-years, [95%CI] |
---|---|---|---|---|---|
Nondysplastic Barrett’s esophagus |
6279 | 3 | 0.5 [0.2–1.4] | 0 | 0 [0–0.6] |
Indefinite dysplasia | 959 | 2 | 2.1 [0.3–7.5] | 0 | 0 [0–3.8] |
Low grade dysplasia | 2802 | 11 | 3.9 [2.0–7.0] | 0 | 0 [0–1.3] |
High grade dysplasia | 2782 | 84 | 30.2 [24.1–37.4] | 6 | 2.2 [0.8–4.7] |
Total, nonmalignant | 12 822 | 100 | 7.8 [6.3–9.5] | 6 | 0.5 [0.2–1.0] |
Intramucosal adenocarcinoma |
498 | -- | -- | 2 | 4.0 [0.5–14.5] |
Invasive adenocarcinoma |
163 | -- | -- | 0 | 0 [0–22.6] |
Total | 13 483 | -- | -- | 8 | 0.6 [0.3–1.2] |
EAC, esophageal adenocarcinoma; CI, confidence interval.