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. Author manuscript; available in PMC: 2014 Aug 25.
Published in final edited form as: J Am Coll Cardiol. 2014 Aug 19;64(7):696–706. doi: 10.1016/j.jacc.2014.04.068

Figure 6. Gsk3α deletion promotes E2F-1 recruitment in vivo.

Figure 6

(A) Representative immunoblots show phospho-Retinoblastoma protein (pRb) (Ser790) and E2F-1 from 3 wk post-MI LV lysates. (B) Quantification shows comparable pRb and significantly increased levels of E2F-1 in the post-MI KO hearts, n=4-5. Results are expressed as mean±SEM, ** P<0.01. (C) Co-immunoprecipitation using an antibody against E2F-1 followed by immunoblotting for GSK-3α in neonatal rat ventricular myocytes (NRVM) confirms a physical interaction between these molecules.