Figure 4. Decreased reactive astrocytosis in MEM-treated animals.
A,B,C.Representative GFAP inmuhistochemistry from sham-, vehicle- and MEM-treated groups 28 days after photothrombosis. A1-6: regions of interest; *infarct core; arrows: glial scar. D.There was a significant reduction in percent area occupied by GFAP-positive cells in MEM- compared to vehicle-treated animals (significant differences indicated by asterisks). Inset: no significant difference in the area of the glial scar between MEM- and vehicle-treated animals (One-way ANOVA with post-hoc Tukey Test *p<0.05, **p<0.01, ***p<0.001; 4 animals; >/=6 sections each per group).