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. 2014 Jul 18;7(9):1069–1081. doi: 10.1242/dmm.016873

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© 2014. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 2. — Hits from the neutrophil-recruitment anti-inflammatory screen. (A) Example read-out from the neutrophil-recruitment anti-inflammatory screen revealing the hits hesperetin (flavanoid), dexamethasone (corticosteroid), glipizide (antidiabetic) and tetracycline HCl (antibacterial). *P<0.05; **P<0.01. (B) Hits categorized by significance of effect on neutrophil recruitment, when compared with DMSO (−ve) controls. (C) Hits categorized by therapeutic group. The category ‘Other’ represents therapeutic groups containing <six hits. (D) The numbers and proportion of cox inhibitors (NSAIDs), corticosteroids, vasodilator/antihypertensive and antibacterial drugs screened that demonstrated a significant effect on neutrophil recruitment.