TABLE 1.

Baseline Demographics

Variable	Patients, n = 343	Controls, n = 42
Sex
Female	234	26
Male	109	16
Age, yr	43.2 ± 9.6	40.5 ± 10.0
Disease duration, yr	9.1 ± 8.0	—
Clinical subtype
CIS	49	—
RRMS	263	—
SPMS	20	—
PPMS	11	—
EDSS	2 (0–7.5)	—
MSFC, z score	0.20 ± 0.59	—
Subjects on DMT	226	—

Number for categorical variables, mean ± standard deviation for continuous variables, and median (range) for EDSS. CIS = clinically isolated syndrome; DMT = disease-modifying therapy; EDSS = Expanded Disability Status Scale; MSFC = Multiple Sclerosis Functional Composite; PPMS = primary progressive multiple sclerosis; RRMS = relapsing-remitting multiple sclerosis; SPMS = secondary progressive multiple sclerosis.