Table 1.
Demographics and clinical variables | Control | n-3 PUFA | p-value |
---|---|---|---|
Total n | 12 | 12 | — |
Age (years) | 63.1±8.4 | 65.8±9.9 | 0.81 |
Female sex, n (%) | 3 (25) | 5 (42) | 0.41 |
Race (C/AA) | 9/3 | 11/1 | 0.3 |
BMI | 32.0±7.8 | 30.2±7.0 | 0.61 |
HbA1c | 5.9±0.8 | 6.1±1.6 | 0.67 |
HDL | 40.2±11.8 | 41.0±13.1 | 0.89 |
LDL | 105.9±38.9 | 88.1±26.2 | 0.22 |
Triglycerides | 170.8±62.9 | 136.1±43.2 | 0.14 |
LVEF (%) | 55.8±7.6 | 57.3±6.8 | 0.64 |
Hypertension, n (%) | 9 (75) | 9 (75) | 1 |
Diabetes, n (%) | 2 (16) | 3 (25) | 0.63 |
Intraoperative characteristics | |||
CABG only, n (%) | 7 (47) | 6 (50) | 0.7 |
CABG+Valve repair/replace, n (%) | 2 (16) | 3 (25) | 0.63 |
Valve repair/replace, n (%) | 3 (25) | 3 (25) | 1 |
CPB Time (min) | 98.5±20.0 | 101.1±17.2 | 0.74 |
Cross-clamp time (min) | 86.1±18.1 | 87.8±14.1 | 0.8 |
Preoperative medications–N (%) | |||
Aspirin | 9 (75) | 10 (83) | 0.78 |
β-Blocker | 10 (83) | 10 (83) | 1 |
Anti-depressant | 1 (8) | 2 (16) | 0.56 |
Statin | 3 (25) | 2 (16) | 0.63 |
Calcium channel blocker | 1 (8) | 1 (8) | 1 |
ACE Inhibitor/ARB | 8 (66) | 5 (42) | 0.24 |
Insulin | 1 (8) | 1 (8) | 1 |
Biguanides | 0 | 1 (8) | 0.69 |
Postoperative events | |||
Postoperative AF | 4 (33) | 2 (16) | 0.37 |
Hospitalization LOS (days) | 7.4±3.4 | 6.6±2.9 | 0.53 |
Inotropic Support | 2 (16) | 1 (8) | 0.56 |
Other Complications, n (%) | 1 (8) | 2 (16) | 0.56 |
Values for continuous variables expressed as mean±SD. Tests of statistical significance were performed using unpaired Student's t-test for continuous variables, or Fisher's exact test for categorical variables. C, Caucasian; AA, African American; BMI, body mass index; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein; LVEF, left ventricular ejection fraction; CPB, cardiopulmonary bypass; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; AF, atrial fibrillation; LOS, length of stay.