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Several miRNA participate in the induction of the Warburg effect. MiR-155 supports HK-II up-regulation by suppressing C/EBPb, which activates the transcription of the HK-II suppressor miR-143. MiR-15a suppresses the Warburg effect by targeting the glycolytic enzymes aldolase A (AldoA) and triosephosphate isomerase I (TPI1).
