Fig. 1.

Metagenomic profiling of the enrichment process in medium with lactate as the sole carbon source. (A) Enrichment of Dehalococcoides (Dhc, in red) from PCB dechlorinating cultures via a single transfer with PCE as an alternative electron acceptor. Stacked bar graph depicts microbial community compositions (obtained by Illumina sequencing of 16S rRNA genes) at the phylum level. See Fig. S1B for corresponding graphs at the genus level. (B) Retention of potential rdhA gene fragments when changing the electron acceptor from PCBs to PCE in culture CG-1 (58 fragments), CG-4 (15 fragments), and CG-5 (33 fragments). FC, fold change of normalized metagenomic read abundance between PCB-fed and PCE-fed cultures.