. 2014 Aug 4;111(33):12121–12126. doi: 10.1073/pnas.1406886111

Table 2.

Fitness estimates for single mutations

Mutant	Fitness estimate
Mutant	18 °C^a	20 °C^b	37 °C^b	42 °C^b
rpoB I966S	−0.035 (0.043)	0.929 (±0.068)*	0.990 (±0.155)	1.373 (±0.188)*
rpoB I572F	−0.206 (-0.089)*	0.910 (±0.060)*	0.956 (±0.117)	1.170 (±0.135)*
rpoB I572L	−0.308 (-0.132)*	0.928 (±0.047)*	0.954 (±0.067)•	1.176 (±0.138)*
rpoB I572N	−0.229 (-0.073)*	0.946 (±0.074)•	1.003 (±0.104)	1.172 (±0.154)*
rho I15N	0.022 (0.091)	1.018 (±0.079)	1.000 (±0.010)	0.949 (±0.272)

^{^a}

Mean absolute fitness with 95% upper limit CI. An asterisk corresponds to an absolute fitness ${\bar{w}}_{a}$ significantly <0.00.

^{^b}

Mean relative fitness ± 95% CI. The asterisks represent significant deviation from the null hypothesis that mean fitness equals 1.0, with one asterisk denoting significance at P < 0.05 and a dot denoting 0.05 < P < 0.1.