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. 2014 Sep;4(9):a017855. doi: 10.1101/cshperspect.a017855

Figure 11.

Figure 11.

Adult-type disease (Gie 2003; Marais et al. 2004b). This type of disease manifestation is not seen in young children, emerges with the onset of puberty at ∼8–10 yr of age, and seems to be associated with an excessive and poorly regulated immune response (excessive hypersensitivity type response). Any child with cavitary disease is infectious (as infectious as an adult sputum smear-positive case) and should be regarded as a potential source case.