Table 3.
Disease spectrum documented in children treated for TB in a highly endemic area
| TB manifestation | Total (%) N = 439 |
|---|---|
| Not TB | 85 (19.4) |
| Intrathoracic TB | 307 (69.9) |
| Ghon focus | |
| Uncomplicated (with/without hilar adenopathy) |
16/307 (5.2) |
| Complicated | 3/307 (1.0) |
| Lymph node disease | |
| Uncomplicated | 147/307 (47.9) |
| Complicated | |
| Compression | 25/307 (8.1) |
| Consolidation | 62/307 (20.6) |
| Pleurisy | 24/307 (7.8) |
| Pericarditis | 1/307 (0.3) |
| Disseminated (miliary) disease | 15/307 (4.9) |
| Adult-type disease | 14/307 (4.6) |
| Extrathoracic TB | 72 (16.4) |
| Peripheral lymphadenitis | |
| Cervical | 35/72 (48.6) |
| Other | 1/72 (1.4) |
| Central nervous system TB | |
| Meningitis | 14/72 (19.4) |
| Tuberculoma | 2/72 (2.8) |
| Abdominal TB | 1/72 (1.4) |
| Osteoarticular TB | |
| Vertebral spondylitis | 4/72 (5.6) |
| Other | 7/72 (9.7) |
| Skin | 8/72 (11.1) |
| Intra- + Extrathoracic TB | [25 (5.7)] |
Data adapted from Marais et al. 2006a.TB, tuberculosis; Not TB, chest radiograph not suggestive of TB (confirmed by two independent child TB experts), no bacteriologic or histologic proof and no extrathoracic TB recorded; Intra- + extrathoracic TB, intra- and extrathoracic TB, included in both groups.