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. Author manuscript; available in PMC: 2014 Aug 25.
Published in final edited form as: Nat Struct Mol Biol. 2014 Jan 5;21(2):152–159. doi: 10.1038/nsmb.2741

Figure 1.

Figure 1

Cryo-EM 3D reconstruction of EttA-EQ2-bound PRE complex. Overview of the segmented cryo-EM map of EttA-EQ2-bound PRE complex reconstructed from Class I. (a) Back view showing the tRNA exit site; (b) front view showing the tRNA entry site; (c) top view; (d) intersubunit interface view from the 50S side, with 50S subunit computationally removed; (e) intersubunit interface view from the 30S side, with 30S subunit computationally removed. A-tRNA and P-tRNA, short for A-site tRNA and P-site tRNA, respectively. Abbreviations of landmarks: hd, 30S subunit head; bk, 30S subunit beak; sp, 30S subunit spur; h17, helix 17 of 16S rRNA; cp, central protuberance of 50S subunit; st, stalk; H68, H69, Helix 68 and 69 of 23S rRNA, respectively; ABC, ATP-binding cassette domain; PtIM, short for P-site tRNA interaction motif, also called inter-ABC-domain linker of EttA; arm, the arm of EttA, an α-helical ABC1 domain of EttA.