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. 2014 Aug 25;9(8):e98673. doi: 10.1371/journal.pone.0098673

Table 3. Multivariate prognostic analysis of DFS and OS.

Characteristics DFS OS
P value HR(95%CI) P value HR(95%CI)
AJCC T Stage 0.961 0.992
1 1 1
2 0.925(0.413–2.069) 0.939(0.302–2.920)
3–4 0.800(0.140–4.564) 0.901(0.074–10.997)
AJCC N Stage 0.930 0.817
0 1 1
1 1.058(0.430–2.607) 0.829(0.203–3.384)
2 1.150(0.309–4.272) 1.852(0.371–9.250)
3 1.708(0.351–8.300) 1.433(0.156–13.136)
Grade 0.212 0.768
1 1 1
2 2.429(0.903–6.531) 1.618(0.441–5.930)
3 1.815(0.558–5.905) 1.321(0.281–6.212)
Subtype 0.012* 0.043*
LA 1 1
LB 0.363 1.564(0.597–4.096) 0.316 2.153(0.480–9.652)
TN 0.033 2.809(1.086–7.264) 0.037 4.382(1.095–17.535)
HER2+ 0.002 5.221(1.788–15.240) 0.009 8.645(1.715–43.587)
CHD1L over-expression 0.042* 0.479
Absense 1 1
Presence 2.169(1.029–4.573) 0.663(0.212–2.069)

*, statistically significant.

Abbreviations: DFS, disease free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval; LA, luminal A; LB, luminal B; TN, triple negative; HER2, human epidermal growth factor receptor 2.