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. Author manuscript; available in PMC: 2014 Aug 25.
Published in final edited form as: Cancer Gene Ther. 2011 Aug 26;18(12):850–858. doi: 10.1038/cgt.2011.54

Figure 5.

Figure 5

Effects of ODN1826 (ODN) on lymph node cells in wild-type (WT) and CEA-Tg mice. MC38 tumor cells were implanted s.c. on day 1 into C57Bl/6 wild-type and CEA-Tg mice. Groups of mice were treated with ODN on days 8 and 10. NT = no treatment control. Draining lymph nodes were harvested on day 15. The number of CD11b+ monocyte/macrophages, B220+ B cells, CD4+FoxP3+ Treg cells, CD11b+Gr1+ MDSC, CD11c+CD11b+ mDC, CD11c+B220+ pDC, and CD11c+CD86+ aDC were assessed by flow cytometry. Data represent means ± SD, n = 4 mice per group. * = P < 0.05, ODN versus NT; ** P < 0.05, WT versus CEA-Tg.