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. 2014 Aug 25;9(8):e104804. doi: 10.1371/journal.pone.0104804

Figure 1. Involvement of TLRs on human DC maturation during H. pylori infection.

Figure 1

Human monocyte-derived DCs were pre-incubated wit TLR-neutralizing antibodies for 1 h. Afterwards, DCs were infected with H. pylori G27 (MOI 5) and the levels of the costimulatory molecule CD86 and the maturation marker CD83 were analyzed by FACS on CD11c+ cells 24 h post-infection. Data are presented as mean ± SD of five independent experiments. *p≤0.05, **p≤0.005, ***p≤0.0005. Asterisks on top of bars indicate significance relative to non-neutralized, H. pylori-primed control cells.