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. Author manuscript; available in PMC: 2014 Aug 25.
Published in final edited form as: Oral Oncol. 2007 Dec 3;44(8):753–758. doi: 10.1016/j.oraloncology.2007.08.019

Figure 1.

Figure 1

RT-PCR amplifications of the WWOX cDNA of oral leukoplasia (OL) cases. (a) Electrophoresis in polyacrylamide gel 6.5% was used to detect wild-type transcript (1284 bp) and alterations in the WWOX mRNA transcripts. Absence of transcript was seen in 1 lesion (#OL22). Representative sequences from the OLs showing five different types of aberrant transcripts: #OL2 (b); #OL14 (c); #OL18 (d); two in #OL23 – < (e) and > (f) bands. * represents a partial loss of the exon. In case #OL16 we detected a band of abnormal size and we sequenced the exons 1–6 and part of exon 7 but the aberrant transcript was not possible detected because of minute sample amount. WT – Normal WWOX transcription RNA with 9 exons.