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. Author manuscript; available in PMC: 2014 Aug 25.
Published in final edited form as: AIDS. 2013 Jul 31;27(12):1959–1970. doi: 10.1097/QAD.0b013e328361195b

Table 2.

Estimated Mean Ages in Years (and 95% Confidence Intervals) at Pubertal Onset by HIV Infection status and Race/Ethnicity for Perinatally HIV-exposed Youth from the IMPAACT 219C and PHACS AMP Studies.

Girls Boys
Breast (N=1222) Pubic hair (N=1185) Genitalia (N=1259) Pubic Hair (N=1182)
Estimated Mean (95 % CI) Estimated Mean (95 % CI) Estimated Mean (95 % CI) Estimated Mean (95 % CI)
By HIV Infection Status
 HIV-exposed uninfected 9.61 (9.38, 9.84) 9.98 (9.72, 10.23) 10.36 (10.09, 10.63) 10.72 (10.43, 11.01)
 HIV-infected 10.28 (10.18, 10.38)** 10.46 (10.34, 10.57)** 11.25 (11.13, 11.36)** 11.54 (11.42, 11.66)**
By Race/Ethnicity
 White Non-Hispanic 10.75 (10.49, 11.01) 11.01 (10.73, 11.29) 11.68 (11.36, 12.00) 12.07 (11.74, 12.40)
 Black Non-Hispanic 9.92 (9.80, 10.05)** 10.03 (9.90, 10.16)** 10.90 (10.76, 11.05)** 11.19 (11.04, 11.34)**
 Hispanic 10.42 (10.24, 10.60)* 10.80 (10.61, 10.99) 11.29 (11.09, 11.48)* 11.59 (11.38, 11.79)*
 Other/Unknown 9.75 (9.13, 10.37)* 10.29 (9.66, 10.91)* 11.15 (10.31, 12.00) 11.64 (10.76, 12.51)
By Race/Ethnicity and HIV Infection Status
Among HIV-exposed Uninfected (n=218) (n=216) (n=226) (n=210)
 White Non-Hispanic 10.48 (9.81, 11.16) 11.27 (10.44, 12.10) 11.61 (10.68, 12.54) 11.92 (10.89, 12.95)
 Black Non-Hispanic 9.15 (8.85, 9.45)** 9.55 (9.20, 9.89)** 10.03 (9.69,10.36)* 10.43 (10.03, 10.82)*
 Hispanic 9.95 (9.56, 10.35) 10.15 (9.71, 10.58)* 10.40 (10.00,10.81)* 10.80 (10.33, 11.27)*
 Other/Unknown 9.93 (8.75, 11.11) 11.07 (9.60, 12.53) N/A N/A
Among Perinatally HIV-infected (n=1004) (n=969) (n=1031) (n=970)
 White Non-Hispanic 10.78 (10,51, 11.06) 10.97 (10.68, 11.27) 11.67 (11.34, 12.00) 12.08 (11.74, 12.42)
 Black Non-Hispanic 10.06 (9.93, 10.20)** 10.11 (9.97, 10.25)** 11.04 (10.89, 11.19)** 11.30 (11.14, 11.46)**
 Hispanic 10.52 (10.33, 10.71) 10.95 (10.74, 11.15) 11.47 (11.26, 11.68) 11.75 (11.53, 11.97)
 Other/Unknown 9.69 (9.00, 10.39)* 10.11 (9.42, 10.79)* 11.07 (10.23, 11.91) 11.57 (10.69, 12.44)

Statistical comparisons with reference group (listed first within group) indicated by ** denoting p<0.001 and *denoting p<0.05. CI=confidence interval